Flooding is identified as the most frequent type of natural disaster that affects lives and property in vulnerable areas. Changes in climate and land use patterns affect water availability and run-off, which alters the flood regimes of rivers. Various structural and non-structural countermeasures are required to mitigate flood events and their effects. These flood risk reduction measures require a detailed understanding of flood inundation characteristics at various locations within the target area. The impacts of urbanization and climate change on flood risk in rapidly growing cities of Southeast Asia for crafting sustainable urban water environment strategies were assessed. A number of flood inundation simulations were carried out considering multiple GCMs/RCPs, land use and countermeasures available in local master plan.